Evaluation of DNA Binding, Cleavage, and Cytotoxic Activity of Cu(II), Co(II), and Ni(II) Schiff Base Complexes of 1-Phenylindoline-2,3-dione with Isonicotinohydrazide
Figure 5
Absorption spectra of (a) Cu(II) and (b) Co(II) complexes in the absence and in the presence of the CT-DNA. [complex] = 30 M, [DNA] = 0 to 30 M. The arrow indicates absorption intensity decrease with increasing addition of the CT-DNA. Plots of [DNA]/() versus [DNA] for the complexes with CT-DNA. The arrow indicates absorption intensity decrease with increasing addition of the CT-DNA.
