Evaluation of DNA Binding, Cleavage, and Cytotoxic Activity of Cu(II), Co(II), and Ni(II) Schiff Base Complexes of 1-Phenylindoline-2,3-dione with Isonicotinohydrazide

<table>Treatment of complexes that exert an antiproliferative effect on liver cancer cell line. HepG2 cells were treated with complexes (Cu, Co, and Ni) for 48 h. Control received appropriate carriers. Cell viability was assessed by MTT cell proliferation assay.</table>

Bioinorganic Chemistry and Applications

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Figure 9

Figure 9: Evaluation of DNA Binding, Cleavage, and Cytotoxic Activity of Cu(II), Co(II), and Ni(II) Schiff Base Complexes of 1-Phenylindoline-2,3-dione with Isonicotinohydrazide 

Figure 9 | Evaluation of DNA Binding, Cleavage, and Cytotoxic Activity of Cu(II), Co(II), and Ni(II) Schiff Base Complexes of 1-Phenylindoline-2,3-dione with Isonicotinohydrazide 