Research Article
Syntheses, Characterization, Resolution, and Biological Studies of Coordination Compounds of Aspartic Acid and Glycine
Table 4
Cytotoxic activity of the parent and resolved compounds.
| Compound | | LC50 (95% confidence Interval) (ug/mL) |
| Na[Cu(L1)3] | P | 7.492 (0.003–19.817) | R | 4.691 (0.225–10.25) | Na[Co(L1)3] | P | 4.576 (0.001–12.64) | R | 4.550 (0.001–12.64) | Na[Ni(L1)3] | P | 4.187 (0.000–13.04) | R | 8.044 (0.477–17.49) | Na[Co(L2)3] | P | 7.432 (0.882–14.92) | R | 4.775 (−) | L1 | | 6.942 (1.007–13.478) | L2 | | 13.867 (2.411–28.421) | K2Cr2O7 (Standard) | | 3.377 (1.479–4.505) |
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Values expressed as L50 values (95% confidence interval). P: parent compound; R: resolved compound.
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