Structure-Based Drug Design for Cytochrome P450 Family 1 Inhibitors

<div>ANF bound in the active site of CYP1A1 (PDB ID: 4I8V). ANF: black carbon atoms; conserved phenylalanines 123, 224, and 258: light green; selected nonconserved residues: Ser122, Asn222, Phe319, and Val382.</div>

Bioinorganic Chemistry and Applications

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Figure 2

Figure 2: Structure-Based Drug Design for Cytochrome P450 Family 1 Inhibitors 