Structure-Based Drug Design for Cytochrome P450 Family 1 Inhibitors

<div>ANF bound in the active site of CYP1A2 (PDB ID: 2HI4). ANF: black carbon atoms; conserved phenylalanines 125, 226, and 260: light green; selected nonconserved residues: Thr124, Thr223, Phe319, and Leu382.</div>

Bioinorganic Chemistry and Applications

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Figure 3

Figure 3: Structure-Based Drug Design for Cytochrome P450 Family 1 Inhibitors 