Review Article

Structure-Based Drug Design for Cytochrome P450 Family 1 Inhibitors

Figure 4

ANF bound in the active site of CYP1B1 (PDB ID: 3PM0). ANF: black carbon atoms; conserved phenylalanines 134, 231, and 268: light green; selected nonconserved residues: Ala133, Asn228, Gln332, and Val395.