Synthesis of Novel VO(II)-Perimidine Complexes: Spectral, Computational, and Antitumor Studies

Table 10

IC₅₀ of some tested compounds against liver (HepG2), breast (MCF-7), and colon (HCT116) cancer cell lines.

Cell type	IC50 (µg/ml)
	L^1	VO(II)-L^1	L^2	VO(II)-L^2	L^3	VO(II)-L^3	L^4	VO(II)-L^4	L^5	VO(II)-L^5	Doxorubicin
MCF-7	19.68	23.06	25.92	93.92	15.50	>100	24.96	3.42	11.44	>100	0.60
HepG2	19.79	19.94	27.23	55.67	11.01	>100	28.25	1.27	9.91	>100	0.34
HCT116	19.15	22.93	13.27	95.17	15.53	>100	26.24	1.66	23.30	>100	0.39