Research Article
Synthesis of Novel VO(II)-Perimidine Complexes: Spectral, Computational, and Antitumor Studies
Table 10
IC50 of some tested compounds against liver (HepG2), breast (MCF-7), and colon (HCT116) cancer cell lines.
| Cell type | IC50 (µg/ml) | L1 | VO(II)-L1 | L2 | VO(II)-L2 | L3 | VO(II)-L3 | L4 | VO(II)-L4 | L5 | VO(II)-L5 | Doxorubicin |
| MCF-7 | 19.68 | 23.06 | 25.92 | 93.92 | 15.50 | >100 | 24.96 | 3.42 | 11.44 | >100 | 0.60 | HepG2 | 19.79 | 19.94 | 27.23 | 55.67 | 11.01 | >100 | 28.25 | 1.27 | 9.91 | >100 | 0.34 | HCT116 | 19.15 | 22.93 | 13.27 | 95.17 | 15.53 | >100 | 26.24 | 1.66 | 23.30 | >100 | 0.39 |
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