Structural Basis for pH-Dependent Oligomerization of Dihydropyrimidinase from Pseudomonas aeruginosa PAO1

Figure 6

Comparison of the tetrameric structures of Thermus sp. dihydropyrimidinase and P. aeruginosa dihydropyrimidinase. (a) Structural analysis of the dimer-dimer interface of P. aeruginosa dihydropyrimidinase. The distance (Å) of the residues is shown. (b) Many residues crucial for forming hydrogen bonds at the dimer-dimer interface of P. aeruginosa dihydropyrimidinase were not found in the dimer-dimer interface of Thermus sp. dihydropyrimidinase.

(a)

(b)