Occurrence and Impact of Minor Histocompatibility Antigens' Disparities on Outcomes of Hematopoietic Stem Cell Transplantation from HLA-Matched Sibling Donors

Table 1

Autosomally encoded MiHA.

MiHA	Restriction	Identification	Clinical trials	Protein	Tissue distribution	Presence on cells
HA-1	HLA-A*02	Den Haan et al. 1998 [14]	Goulmy et al. 1996   [15]; Tseng et al. 1999 [16]  Gallardo et al. 2001 [17]	HA-1	Restricted	Hematopoietic cells; Bronchial carcinomas; Cervix carcinoma; Breast carcinoma; Prostate carcinoma
HA-1/B60	HLA-B*60	Mommaas et al. 2002 [18]	—	HA-1	Restricted	Hematopoietic cells
HA-2	HLA-A*02	Den Haan et al. 1995 [19]	Goulmy et al. 1996 [15]	Myosin 1G	Restricted	Hematopoietic cells
HA-3	HLA-A*01	Spierings et al. 2003 [20]	Tseng et al. 1999 [16]	Lymphoid blast crisis oncogene	Broad	Hematopoietic cells; Keratinocytes; Fibroblasts; PTECs; HUVECs; Melanocytes
HA-8	HLA-A*02	Brickner et al. 2001 [21]	Akatsuka et al. 2003 [22]; Pérez-García et al. 2005 [23]	KIAA0020	Broad	Hematopoietic cells; Fibroblasts
HB-1^H/Y	HLA-B*44	Dolstra et al. 1999 [24]	—	Unknown	Restricted	B cell ALL, EBV-BLCLs
ACC-1	HLA-A*24	Akatsuka et al. 2003 [25]	Nishida et al. 2004 [26]	BCL2A1	Restricted	Hematopoietic cells
ACC-2	HLA-B*44	Akatsuka et al. 2003 [25]	—	BCL2A1	Restricted	Hematopoietic cells
SP110 (HwA-9)	HLA-A*03	Warren et al. 2006 [13]	—	SP110 intranuclear protein	Restricted	Hematopoietic cells; IFN—gamma inducible
PANE1 (HwA-10)	HLA-A*03	Brickner et al. 2006 [27]	—	PANE1	Restricted	Lymphoid cells
UGT2B17/A29	HLA-A*29	Murata et al. 2003 [28]	—	UGT2B17	Restricted	Dendritic cells, B-cells, EBV-BLCLs
UGT2B17/B44	HLA-B*44	Terrakura et al. 2007 [29]		UGT2B17	Restricted	Dendritic cells, B-cells, EBV-BLCLs