Clinical Study

Occurrence and Impact of Minor Histocompatibility Antigens' Disparities on Outcomes of Hematopoietic Stem Cell Transplantation from HLA-Matched Sibling Donors

Table 6

Distribution of MiHA genotypes' frequencies in 62 related donor-recipient pairs.

MiHAGenotypeRecipientDonor

HA-1HH13.1%16.4%
HR50.8%50.8%
RR36.1%32.8%
HA-2VV59.0%50.8%
VM39.3%44.3%
MM1.6%4.9%
HA-3TT44.3%47.5%
TM47.5%45.9%
MM8.2%6.6%
HA-8RR27.9%27.9%
RP36.1%36.1%
PP36.1%36.1%
HB-1HH34.4%36.1%
HY55.7%57.4%
YY9.8%6.6%
ACC-1YY4.9%1.6%
YC36.1%37.7%
CC59.0%60.7%
ACC-2DD3.3%0.0%
DG34.4%39.3%
GG62.3%60.7%
SP110
(HwA9)
RR27.9%31.1%
RG60.7%54.1%
GG11.5%14.8%
PANE1 (HwA10)RR42.6%42.6%
R*49.2%52.5%
** 8.2%4.9%

++ or +− genotypes’ frequencies of UGT2B17 and HY are equal to the frequency of alleles + and their − − genotypes’ frequencies are equal to the frequency of alleles − presented in Table 5.