Differential Expression of Matrix Metalloproteinase-2 Expression in Disseminated Tumor Cells and Micrometastasis in Bone Marrow of Patients with Nonmetastatic and Metastatic Prostate Cancer: Theoretical Considerations and Clinical Implications—An Immunocytochemical Study

Table 1

Demographic characteristics of the study group.

	Group 1	Group 2
Patient number (𝑛)	185	30
Mean age ± SD (years) at sampling	72.2 ± 9.0	76.4 ± 8.7
Median serum PSA (IQR) (ng/mL) at sampling	1,32 (0,01–5,77)	43,81 (27,72–150)
Median Gleason score at diagnosis (IQR)	6 (5–7)	6 (5–7)
Median stage at diagnosis (IQR)	3 (2-3)	3 (2-3)
Median time from diagnosis (IQR) (years)	3 (1–7)	6 (4–9)
% (𝑛) detection of prostate cells
CPCs	62.7% (116)	100% (30)
DTCs	62.2% (115)	100% (30)
mM	71.4% (132)	100% (30)

IQR: interquartile range, CPCs: circulating prostate cells, and DTC: disseminated tumor cells.