Inhibition of Mammalian Target of Rapamycin in Human Acute Myeloid Leukemia Cells Has Diverse Effects That Depend on the Environmental In Vitro Stress
Figure 3
Effects of in vitro culture of primary human AML cells on mTOR signaling for primary human AML cells derived from unselected patients. The figure compares mTOR-mediated signaling (levels of the downstream target p-S6RP) for AML cells incubated for 24 hours in serum-free (a) or FBS-containing (b) medium alone or in the presence of rapamycin 100 nM. The results are presented as the median fluorescence intensity (MFI).
