Bone Marrow Research / 2012 / Article / Tab 2 / Research Article
Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal Cord Injury Patients of Different Age Groups: A Comparative Analysis Table 2 Data of the quantity of Bone Marrow Mononuclear Cells (BMMNC) and CD34+ Hematopoietic Stem Cells (HSC) from the literatures based on our search.
S. No. Author Year of Publication No. of Samples Patients or Donors Parameters assessed Mean Quantity of MNC/ml Mean CD34% Mean CD34+ cell count 1 Ema et al. [32 ] 1990 12 Donors CD34% NA 1.05% ± 0.44%* 2 Chernykh et al. [21 ] 2006 10 Donors MNC, count and CD34% 7.5 ± 2.2 × 106 5.40 ± 1.35 3 Chernykh et al. [21 ] 2006 16 Spinal Cord injury Patients MNC count and CD34 percentage 11.0 ± 1.1 × 106 5.4 ± 0.6 4 Mohamadnejad et al. [33 ] 2007 4 Liver Cirrhosis patients MNC and CD34 percentage 3.13 × 108 5.25 × 106 5 Hernández et al. [34 ] 2007 12 Critical limb Ischemia patients MNC and CD34+ cell counts 1.74 ± 1.23 × 109 in group A (Separation done using blood cell separator) and 2.47 ± 1.48 × 109 in group B (Separation done by density gradient by Ficoll-Hypaque) 8.14 ± 6.67 × 107 in group A and 7.90 ± 5.46 × 107 in group B 6 Kaparthi et al. [35 ] 2008 5 Cardiac Disease patients MNC and CD34+ cell count and percentage 9.16 × 107 0.348 3.68 × 105 7 Harting et al. [36 ] 2009 36 10 paediatric and 26 adult Non-cancer patients MNC counts Paediatric patients −2.1 × 106 /mL and in older patients −3.2 × 106 /mL 8 Zhang et al. [16 ] 2010 104 Donors CD34+ cell count and Circulating Immature Cells (CIC) count CIC = 9· 4 (4· 3–21· 1) × 109 L−1 Total CD34+ cell count (×106 ) is 395· 7 (102–1282) 9 Perseghin and Incontri [37 ] 2010 10 Patients-nine with chronic GvHD and one with bullous pemphigoid MNC 5.9 ± 2.19 × 109 in the separation done by Spectra cell separator and 5.29 ± 2.39 × 109 in the separation done by Amicus cell separator
* % mentioned is that of gated cells.