Research Article

Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal Cord Injury Patients of Different Age Groups: A Comparative Analysis

Table 2

Data of the quantity of Bone Marrow Mononuclear Cells (BMMNC) and CD34+ Hematopoietic Stem Cells (HSC) from the literatures based on our search.

S. No.AuthorYear of PublicationNo. of SamplesPatients or DonorsParameters assessedMean Quantity of MNC/mlMean CD34%Mean CD34+ cell count

1Ema et al. [32]199012DonorsCD34%NA1.05% ± 0.44%*
2Chernykh et al. [21]200610DonorsMNC, count and CD34%7.5 ± 2.2 × 1065.40 ± 1.35
3Chernykh et al. [21]200616Spinal Cord injury PatientsMNC count and CD34 percentage11.0 ± 1.1 × 1065.4 ± 0.6
4Mohamadnejad et al. [33]20074Liver Cirrhosis patientsMNC and CD34 percentage3.13 × 1085.25 × 106
5Hernández et al. [34]200712Critical limb Ischemia patientsMNC and CD34+ cell counts1.74 ± 1.23 × 109 in group A (Separation done using blood cell separator) and 2.47 ± 1.48 × 109 in group B (Separation done by density gradient by Ficoll-Hypaque)8.14 ± 6.67 × 107 in group A and 7.90 ± 5.46 × 107 in group B
6Kaparthi et al. [35]20085Cardiac Disease patientsMNC and CD34+ cell count and percentage9.16 × 1070.3483.68 × 105
7Harting et al. [36]20093610 paediatric and 26 adult Non-cancer patientsMNC countsPaediatric patients −2.1 × 106/mL and in older patients −3.2 × 106/mL
8Zhang et al. [16]2010104DonorsCD34+ cell count and Circulating Immature Cells (CIC) countCIC = 9·4 (4·3–21·1) × 109 L−1Total CD34+ cell count (×106) is 395·7 (102–1282)
9Perseghin and Incontri [37]201010Patients-nine with chronic GvHD and one with bullous pemphigoidMNC5.9 ± 2.19 × 109 in the separation done by Spectra cell separator and 5.29 ± 2.39 × 109 in the separation done by Amicus cell separator

*% mentioned is that of gated cells.