| | No. patients | 1070 | | | Age > 65 | −246 | | | Non secretory or hyposecretory | −32 | |
| | No. studied | 792 | | | 1987–1998 (%) | 1999–2010 (%) | P | | No. patients | 462 | 330 | | | 96 (21) | 35 (11) | <.01 | | No. | 162 (35) | 272 (82) | <.01 |
| | Response status at 18 mo (%) | | | No. patients | 366 | 295 | | | NR | 57 (16) | | | | PR | 249 (68) | <.01 | | CR | 60 (16) | |
| | Duration of CR | No. (% of CR) | | | >3 years | 43 (72) | 60 (56) | | | >12 years | 13 (22) | n.a. | |
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