Table 1: Patient population (1987–2010).

No. patients1070
Age > 65−246
Non secretory or hyposecretory−32

No. studied792
1987–1998 (%)1999–2010 (%)P
No. patients462330
96 (21)35 (11)<.01
No. 162 (35)272 (82)<.01

Response status at 18 mo (%)
No. patients366295
 NR57 (16)
 PR249 (68)<.01
 CR60 (16)

  Duration of CRNo. (% of CR)
   >3 years43 (72)60 (56)
   >12 years13 (22)n.a.