Clinical Study
Comparing Two Types of Rabbit ATG prior to Reduced Intensity Conditioning Allogeneic Hematopoietic SCT for Hematologic Malignancies
Table 1
Patients, conditioning, and graft characteristics.
| Patients, conditioning, and graft characteristics | ATG-F | Thymoglobulin | | | |
| Age at transplant, median (range, years) | 59 (40–69) | 51 (22–68) | 0.49 | Number of men, (%) | 8 (53) | 9 (60) | 0.72 | Group diagnosis, (%) | | | | AML | 6 (40) | 6 (40) | 1.00 | MDS | 2 (13) | 0 | 0.46 | CMML | 0 | 3 (20) | 0.23 | MF | 1 (7) | 0 | 1.00 | NHL/HD | 5 (33) | 4 (27) | 0.69 | MM | 1 (7) | 1 (7) | 1.00 | Undifferentiated AL | 0 | 1 (7) | 1.00 | Complete remission at transplant, (%) | 15 (100) | 13 (87) | 0.48 | CMV serostatus donor/recipient, (%) | | | | Positive recipient | 11 (73) | 12 (80) | 0.67 | Positive donor | 7 (47) | 8 (53) | 0.72 | Reason for RIC, (%) | | | | Prior autologous SCT | 8 (53) | 8 (53) | 1.00 | Age | 4 (27) | 4 (27) | 1.00 | Other | 3 (20) | 3 (20) | 1.00 | Chemotherapy agents, (%) | | | | Fludarabine-busulfan | 13 (87) | 12 (80) | 0.67 | Fludarabine-melphalan | 2 (13) | 3 (20) | 1.00 | Related donor, (%) | 4 (27) | 5 (33) | 0.69 | HLA-identical | 4 (27) | 5 (33) | 0.69 | Unrelated donor, (%) | 11 (73) | 10 (67) | 0.69 | 0 mismatch | 8 (53) | 6 (40) | 0.46 | ≥1 mismatch | 3 (20) | 4 (27) | 0.67 | Men donor, (%) | 9 (60) | 13 (87) | 0.10 | Sex mismatch in GvHD sense, (%) | 4 (27) | 1 (7) | 0.33 | Partial T cell depletion, (%) | 7 (47) | 9 (60) | 0.46 | T cell dose, median (range, CD3/kg) | 5 (0.35–130) | 5 (0.35–100) | 0.78 | Blood group incompatibility, (%) | | | | Major | 4 (27) | 4 (27) | 1.00 | Minor | 4 (27) | 5 (33) | 0.91 | Posttransplant immunosuppression, (%) | 15 (100) | 15 (100) | 1.00 |
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