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Journal of Biomedicine and Biotechnology
Volume 2004 (2004), Issue 5, Pages 343-345
http://dx.doi.org/10.1155/S111072430440309X
Correspondence article

Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion

1Institute of Nutritional Sciences, Friedrich-Schiller-University Jena, Dornburgerstrasse 29, Jena 07743, Germany
2Institute of Nutritional Sciences, Justus-Liebig-University Giessen, Wilhelmstrasse 20, Giessen 35392, Germany
3IMFORM GmbH International Clinical Research, Birkenweg 14, Darmstadt 64295, Germany

Received 3 March 2004; Revised 7 June 2004; Accepted 15 June 2004

Copyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

In a pilot study with 6 females and 1 male, the metabolism of various cyanidin glucosides after oral administration of elderberry juice was investigated. The anthocyanin metabolites were detected in urinary excretion. After ingestion of a bolus quantity of 3.57 g total anthocyanins in a 150 mL elderberry juice concentrate, 0.053% of the administered dose was excreted in urine as glucosidically bound cyanidins within the first 5 hours. Only 0.003% of the ingested anthocyanin glucosides was excreted as cyanidin glucuronide, suggesting that this conversion step might be of minor importance in urinary excretion.