- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2006 (2006), Article ID 12129, 3 pages
Interplay Between Oxidative Damage, Protein Synthesis, and Protein Degradation in Alzheimer's Disease
Anatomy and Neurobiology, Sanders Brown Center on
Aging, University of Kentucky, Lexington 40536, KY, USA
Received 4 November 2005; Revised 31 January 2006; Accepted 1 February 2006
Copyright © 2006 Jeffrey N. Keller. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- W R Markesbery, “Neuropathological criteria for the diagnosis of Alzheimer's disease,” Neurobiology of Aging, vol. 18, no. 4 suppl, pp. S13–S19, 1997.
- H M Wisniewski and W Silverman, “Diagnostic criteria for the neuropathological assessment of Alzheimer's disease: current status and major issues,” Neurobiology of Aging, vol. 18, no. 4 suppl, pp. S43–S50, 1997.
- J C Morris, “Mild cognitive impairment and preclinical Alzheimer's disease,” Geriatrics, vol. 60, no. 6 suppl, pp. 9–14, 2005.
- R C Petersen, R Doody, A Kurz, et al., “Current concepts in mild cognitive impairment,” Archives of Neurology, vol. 58, no. 12, pp. 1985–1992, 2001.
- J N Keller, F A Schmitt, S W Scheff, et al., “Evidence of increased oxidative damage in subjects with mild cognitive impairment,” Neurology, vol. 64, no. 7, pp. 1152–1156, 2005.
- L M Sayre, M A Smith, and G Perry, “Chemistry and biochemistry of oxidative stress in neurodegenerative disease,” Current Medicinal Chemistry, vol. 8, no. 7, pp. 721–738, 2001.
- M J Picklo, T J Montine, V Amarnath, et al., “Carbonyl toxicology and Alzheimer's disease,” Toxicology and Applied Pharmacology, vol. 184, no. 3, pp. 187–197, 2002.
- Q Ding, W R Markesbery, Q Chen, et al., “Ribosome dysfunction is an early event in Alzheimer's disease,” Journal of Neuroscience, vol. 25, no. 40, pp. 9171–9175, 2005.
- W R Markesbery, R J Kryscio, M A Lovell, et al., “Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment,” Annals of Neurology, vol. 58, no. 5, pp. 730–735, 2005.
- J Wang, S Xiong, C Xie, et al., “Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease,” Journal of Neurochemistry, vol. 93, no. 4, pp. 953–962, 2005.
- B I Giasson, H Ischiropoulos, V M Lee, and J Q Trojanowski, “The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases,” Free Radical Biology and Medicine, vol. 32, no. 12, pp. 1264–1275, 2002.
- P Jenner and C W Olanow, “Understanding cell death in Parkinson's disease,” Annals of Neurology, vol. 44, no. 3 suppl 1, pp. S72–S84, 1998.
- R S Sohal, “ Role of oxidative stress and protein oxidation in the aging process,” Free Radical Biology and Medicine, vol. 33, no. 1, pp. 37–44, 2002.
- B A Bahr and J Bendiske, “The neuropathogenic contributions of lysosomal dysfunction,” Journal of Neurochemistry, vol. 83, no. 3, pp. 481–489, 2002.
- T Grune, K Merker, G Sandig, et al., “Selective degradation of oxidatively modified protein substrates by the proteasome,” Biochemical and Biophysical Research Communications, vol. 305, no. 3, pp. 709–718, 2003.
- N S Langstrom, J P Anderson, H G Lindroos, et al., “Alzheimer's disease-associated reduction of polysomal mRNA translation,” Molecular Brain Research, vol. 5, no. 4, pp. 259–269, 1989.
- K Honda, M A Smith, X Zhu, et al., “Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron,” Journal of Biological Chemistry, vol. 280, no. 22, pp. 20978–20986, 2005.
- B Langley, J M Gensert, M F Beal, et al., “Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents,” Current Drug Targets, vol. 4, no. 1, pp. 41–50, 2005.
- G A Soliman, “The mammalian target of rapamycin signalling network and gene regulation,” Current Opinion in Lipidology, vol. 16, no. 3, pp. 317–323, 2005.
- H Ryu, K Smith, S I Camelo, et al., “Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice,” Journal of Neurochemistry, vol. 93, no. 5, pp. 1087–1098, 2005.