About this Journal Submit a Manuscript Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2006 (2006), Article ID 27601, 8 pages
http://dx.doi.org/10.1155/JBB/2006/27601
Research Article

Parkinson's Disease in Relation to Pesticide Exposure and Nuclear Encoded Mitochondrial Complex I Gene Variants

1Center for Demographic Studies, Duke University, 2117 Campus Drive, PO Box 90408, Durham 27708-0408, NC, USA
2Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan 4111, QLD, Australia

Received 1 December 2005; Revised 28 March 2006; Accepted 17 April 2006

Copyright © 2006 Elizabeth H. Corder and George D. Mellick. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G D Mellick, P A Silburn, J A Prince, and A J Brookes, “A novel screen for nuclear mitochondrial gene associations with Parkinson's disease,” Journal of Neural Transmission, vol. 111, no. 2, pp. 191–199, 2004. View at Publisher · View at Google Scholar
  2. Y Liu and H Yang, “Environmental toxins and alpha-synuclein in Parkinson's disease,” Molecular Neurobiology, vol. 31, no. 1–3, pp. 273–282, 2005. View at Publisher · View at Google Scholar · View at PubMed
  3. S Yu, K Ueda, and P Chan, “Alpha-synuclein and dopamine metabolism,” Molecular Neurobiology, vol. 31, no. 1–3, pp. 243–254, 2005. View at Publisher · View at Google Scholar · View at PubMed
  4. J H Son, H Kawamata, M S Yoo, et al., “Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons,” Journal of Neurochemistry, vol. 94, no. 4, pp. 1040–1053, 2005. View at Publisher · View at Google Scholar · View at PubMed
  5. D G Le Couteur, A J McLean, M C Taylor, B L Woodham, and P G Board, “Pesticides and Parkinson's disease,” Biomedecine & Pharmacotherapy, vol. 53, no. 3, pp. 122–130, 1999. View at PubMed
  6. D G Le Couteur, M Muller, M C Yang, G D Mellick, and A J McLean, “Age-environment and gene-environment interactions in the pathogenesis of Parkinson's disease,” Reviews on Environmental Health, vol. 17, no. 1, pp. 51–64, 2002. View at PubMed
  7. M M Mouradian, “Recent advances in the genetics and pathogenesis of Parkinson disease,” Neurology, vol. 58, no. 2, pp. 179–185, 2002. View at PubMed
  8. M Meulener, A J Whitworth, C E Armstrong-Gold, et al., “Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease,” Current Biology, vol. 15, no. 17, pp. 1572–1577, 2005. View at Publisher · View at Google Scholar · View at PubMed
  9. B Ritz and F Yu, “Parkinson's disease mortality and pesticide exposure in California 1984–1994,” International Journal of Epidemiology, vol. 29, no. 2, pp. 323–329, 2000. View at Publisher · View at Google Scholar · View at PubMed
  10. J A Smeitink, L W van den Heuvel, W J Koopman, L G Nijtmans, C Ugalde, and P H Willems, “Cell biological consequences of mitochondrial NADH: ubiquinone oxidoreductase deficiency,” Current Neurovascular Research, vol. 1, no. 1, pp. 29–40, 2004. View at Publisher · View at Google Scholar · View at PubMed
  11. J A Smeitink, L W van den Heuvel, and S DiMauro, “The genetics and pathology of oxidative phosphorylation,” Nature Reviews. Genetics, vol. 2, no. 5, pp. 342–352, 2001. View at Publisher · View at Google Scholar · View at PubMed
  12. S Sveinbjornsdottir, A A Hicks, T Jonsson, et al., “Familial aggregation of Parkinson's disease in Iceland,” The New England Journal of Medicine, vol. 343, no. 24, pp. 1765–1770, 2000. View at Publisher · View at Google Scholar · View at PubMed
  13. A Solano, M Roig, C Vives-Bauza, et al., “Bilateral striatal necrosis associated with a novel mutation in the mitochondrial ND6 gene,” Annals of Neurology, vol. 54, no. 4, pp. 527–530, 2003. View at Publisher · View at Google Scholar · View at PubMed
  14. C Vives-Bauza, A L Andreu, G Manfredi, et al., “Sequence analysis of the entire mitochondrial genome in Parkinson's disease,” Biochemical and Biophysical Research Communications, vol. 290, no. 5, pp. 1593–1601, 2002. View at Publisher · View at Google Scholar · View at PubMed
  15. N Hattori, H Yoshino, M Tanaka, H Suzuki, and Y Mizuno, “Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease,” Genomics, vol. 49, no. 1, pp. 52–58, 1998. View at Publisher · View at Google Scholar · View at PubMed
  16. A Elbaz, C Levecque, J Clavel, et al., “CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease,” Annals of Neurology, vol. 55, no. 3, pp. 430–434, 2004. View at Publisher · View at Google Scholar · View at PubMed
  17. Y Deng, B Newman, M P Dunne, P A Silburn, and G D Mellick, “Further evidence that interactions between CYP2D6 and pesticide exposure increase risk for Parkinson's disease,” Annals of Neurology, vol. 55, no. 6, p. 897, 2004. View at Publisher · View at Google Scholar · View at PubMed
  18. E H Corder, R Huang, H M Cathcart, et al., “Membership in genetic groups predicts Alzheimer disease,” Rejuvenation Research, vol. 9, no. 1, pp. 89–93, 2006. View at Publisher · View at Google Scholar · View at PubMed
  19. E H Corder and L A Hefler, “Multilocus genotypes spanning estrogen metabolism associated with breast cancer and fibroadenoma,” Rejuvenation Research, vol. 9, no. 1, pp. 56–60, 2006. View at Publisher · View at Google Scholar · View at PubMed
  20. C E Gartner, D Battistutta, M P Dunne, P A Silburn, and G D Mellick, “Test-retest repeatability of self-reported environmental exposures in Parkinson's disease cases and healthy controls,” Parkinsonism & Related Disorders, vol. 11, no. 5, pp. 287–295, 2005. View at PubMed
  21. W M Howell, M Jobs, U Gyllensten, and A J Brookes, “Dynamic allele-specific hybridization. A new method for scoring single nucleotide polymorphisms,” Nature Biotechnology, vol. 17, no. 1, pp. 87–88, 1999. View at Publisher · View at Google Scholar · View at PubMed
  22. J A Prince, L Feuk, W M Howell, et al., “Robust and accurate single nucleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation,” Genome Research, vol. 11, no. 1, pp. 152–162, 2001. View at Publisher · View at Google Scholar · View at PubMed
  23. M A Woodbury and J Clive, “Clinical pure types as a fuzzy partition,” Journal of Cybernetics, vol. 4, pp. 111–121, 1974.
  24. M A Woodbury, J Clive, and A Garson, “Mathematical typology: a grade of membership technique for obtaining disease definition,” Computers and Biomedical Research, vol. 11, no. 3, pp. 277–298, 1978. View at Publisher · View at Google Scholar · View at PubMed
  25. M A Woodbury, K G Manton, and D H Tolley, “A general model for statistical analysis using fuzzy sets: sufficient conditions for identifiability and statistical properties,” Information Sciences, vol. 1, pp. 149–180, 1994. View at Publisher · View at Google Scholar
  26. L M de Lau, P C Giesbergen, M C de Rijk, A Hofman, P J Koudstaal, and M M Breteler, “Incidence of parkinsonism and Parkinson disease in a general population: the Rotterdam Study,” Neurology, vol. 63, no. 7, pp. 1240–1244, 2004. View at PubMed
  27. K G Manton, L S Corder, and E Stallard, “Estimates of change in chronic disability and institutional incidence and prevalence rates in the U.S. elderly population from the 1982, 1984, and 1989 National Long Term Care Survey,” Journal of Gerontology, vol. 48, no. 4, pp. S153–S166, 1993. View at PubMed
  28. A Jablensky and M A Woodbury, “Dementia praecox and manic-depressive insanity in 1908: a Grade of Membership analysis of the Kraepelinian dichotomy,” European Archives of Psychiatry and Clinical Neuroscience, vol. 245, no. 4-5, pp. 202–209, 1995. View at Publisher · View at Google Scholar · View at PubMed
  29. J F Hallmayer, L Kalaydjieva, J Badcock, et al., “Genetic evidence for a distinct subtype of schizophrenia characterized by pervasive cognitive deficit,” American Journal of Human Genetics, vol. 77, no. 3, pp. 468–476, 2005. View at Publisher · View at Google Scholar · View at PubMed
  30. E H Corder, M A Woodbury, K G Manton, and L L Field, “Grade-of-membership sibpair linkage analysis maps the IDDM11 locus to chromosome 14q24.3-q31: a pattern recognition approach to linkage,” Annals of Human Genetics, vol. 65, pp. 387–394, 2001. View at Publisher · View at Google Scholar
  31. E H Corder, M A Woodbury, I Volkmann, D K Madsen, N Bogdanovic, and B Winblad, “Density profiles of Alzheimer disease regional brain pathology for the Huddinge Brain Bank: pattern recognition emulates and expands upon Braak staging,” Experimental Gerontology, vol. 35, no. 6-7, pp. 851–864, 2000. View at Publisher · View at Google Scholar · View at PubMed
  32. E H Corder, J F Ervin, E Lockhart, M H Szymanski, D E Schmechel, and C M Hulette, “Cardiovascular damage in Alzheimer disease: autopsy findings from the Bryan ADRC,” Journal of Biomedicine and Biotechnology, vol. 2005, no. 2, pp. 189–197, 2005. View at Publisher · View at Google Scholar · View at PubMed
  33. S Iivonen, E H Corder, M Lehtovirta, et al., “Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease,” Neurology, vol. 62, no. 7, pp. 1170–1176, 2004. View at PubMed
  34. S Helisalmi, M Hiltunen, S Vepsäläinen, et al., “Genetic variation in apolipoprotein D and Alzheimer's disease,” Journal of Neurology, vol. 251, no. 8, pp. 951–957, 2004. View at Publisher · View at Google Scholar · View at PubMed