- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Annual Issues
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Reviewers Acknowledgment
- Submit a Manuscript
- Subscription Information
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2006 (2006), Article ID 70414, 13 pages
Screening Pesticides for Neuropathogenicity
Health Effects Division (7509C), Office of Pesticide
Programs, United States Environmental Protection Agency, 1200 Pennsylvania Avenue NW, Washington DC 20460, USA
Received 1 December 2005; Revised 18 May 2006; Accepted 30 May 2006
Copyright © 2006 John D. Doherty. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- J W Langston, “The etiology of Parkinson's disease with emphasis on the MPTP story,” Neurology, vol. 47, no. 6 suppl 3, pp. S153–S160, 1996.
- N-S Chu, C-C Huang, and D B Calne, “Manganese,” in Experimental and Clinical Neurotoxicology, P S Spencer, H H Schaumburg, and A C Ludolph, Eds., pp. 752–755, Oxford Press, New York, NY, 2nd edition, 2000.
- T Kiely, D Donaldson, and A Grube, “Pesticide Industry Sales and Usage: 2000 and 2001 Market Estimates,” 2004, Published by Biological and Economic Analysis Division, Office of Pesticide Programs Office of Prevention, Pesticides and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC 20460.
- D J Ecobichon, “Toxic effects of pesticides,” in Casarett and Doull's Toxicology: The Basic Science of Poisons, C D Klassen, Ed., pp. 643–689, McGraw Hill, New York, NY, 5th edition, 1996.
- EPA. 1998. OPPTS Harmonized Test Guidelines Series 870 Health Effects. United States Environmental Protection Agency, Office of Prevention, Pesticides and Toxic Substances, Washington, DC. 20460. http://www.epa.gov/pesticides (See under Science and Policy- Test Guidelines).
- EPA. 2002. A Review of the reference dose and reference concentration processes. Risk Assessment Forum Report dated December 2002.
- D A Cory-Slechta, M Thiruchelvam, B K Barlow, and E K Richfield, “Developmental pesticide models of the Parkinson disease phenotype,” Environmental Health Perspectives, vol. 113, no. 9, pp. 1263–1270, 2005.
- H H Liou, M C Tsai, C J Chen, et al., “Environmental risk factors and Parkinson's disease: a case-control study in Taiwan,” Neurology, vol. 48, no. 6, pp. 1583–1588, 1997.
- G Woodward, “Autism and Parkinson's disease,” Medical Hypotheses, vol. 56, no. 2, pp. 246–249, 2001.
- I Baldi, P Lebailly, B Mohammed-Brahim, L Letenneur, J-F Dartigues, and P Brochard, “Neurodegenerative diseases and exposure to pesticides in the elderly,” American Journal of Epidemiology, vol. 157, no. 5, pp. 409–414, 2003.
- B K Barlow, E K Richfield, D A Cory-Slechta, and M Thiruchelvam, “A fetal risk factor for Parkinson's disease,” Developmental Neuroscience, vol. 26, no. 1, pp. 11–23, 2004.
- J A Firestone, T Smith-Weller, G Franklin, P Swanson, W T Jr Longstreth, and H Checkoway, “Pesticides and risk of Parkinson disease: a population-based case-control study,” Archives of Neurology, vol. 62, no. 1, pp. 91–95, 2005.
- R N Takahashi, R Rogerio, and M Zanin, “Maneb enhances MPTP neurotoxicity in mice,” Research Communications in Chemical Pathology and Pharmacology, vol. 66, no. 1, pp. 167–170, 1989.
- T L Walters, I Irwin, K Delfani, J W Langston, and A M Janson, “Diethyldithiocarbamate causes nigral cell loss and dopamine depletion with nontoxic doses of MPTP,” Experimental Neurology, vol. 156, no. 1, pp. 62–70, 1999.
- T B Sherer, J-H Kim, R Betarbet, and J T Greenamyre, “Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and -synuclein aggregation,” Experimental Neurology, vol. 179, no. 1, pp. 9–16, 2003.
- R Betarbet, T B Sherer, G MacKenzie, M Garcia-Osuna, A V Panov, and J T Greenamyre, “Chronic systemic pesticide exposure reproduces features of Parkinson's disease,” Nature Neuroscience, vol. 3, no. 12, pp. 1301–1306, 2000.
- T B Sherer, R Betarbet, A K Stout, et al., “An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered -synuclein metabolism and oxidative damage,” Journal of Neuroscience, vol. 22, no. 16, pp. 7006–7015, 2002.
- J D Doherty, N Jr Salem, C J Lauter, and E G Trams, “-stimulated ATPase in rat brain,” Neurochemical Research, vol. 8, no. 4, pp. 493–500, 1983.
- L Fleming, J B Mann, J Bean, T Briggle, and J R Sanchez-Ramos, “Parkinson's disease and brain levels of organochlorine pesticides,” Annals of Neurology, vol. 36, no. 1, pp. 100–103, 1994.
- G W Miller, M L Kirby, A I Levey, and J R Bloomquist, “Heptachlor alters expression and function of dopamine transporters,” NeuroToxicology, vol. 20, no. 4, pp. 631–637, 1999.
- F M Corrigan, C L Wienburg, R F Shore, S E Daniel, and D Mann, “Organochlorine insecticides in substantia nigra in Parkinson's disease,” Journal of Toxicology and Environmental Health - Part A, vol. 59, no. 4, pp. 229–234, 2000.
- D A Di Monte, “The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?,” Lancet Neurology, vol. 2, no. 9, pp. 531–538, 2003.
- A Cannas, B Costa, P Tacconi, L Pinna, and A Fiaschi, “Dementia of Alzheimer type (DAT) in a man chronically exposed to pesticides,” Acta Neurologica, vol. 14, no. 3, pp. 220–223, 1992.
- E Gauthier, I Fortier, F Courchesne, P Pepin, J Mortimer, and D Gauvreau, “Environmental pesticide exposure as a risk factor for Alzheimer's disease: a case-control study,” Environmental Research, vol. 86, no. 1, pp. 37–45, 2001.
- C J Burns, K K Beard, and J B Cartmill, “Mortality in chemical workers potentially exposed to 2,4-dichlorophenoxyacetic acid (2,4-D) 1945-94: an update,” Occupational and Environmental Medicine, vol. 58, no. 1, pp. 24–30, 2001.
- V McGuire, W T Jr Longstreth, L M Nelson, et al., “Occupational exposures and amyotrophic lateral sclerosis: a population- based case-control study,” American Journal of Epidemiology, vol. 145, no. 12, pp. 1076–1088, 1997.
- G A Jamal, S Hansen, and P OO Julu, “Low level exposures to organophosphorus esters may cause neurotoxicity,” Toxicology, vol. 181-182, pp. 23–33, 2002.
- H PM Van Helden, R AP Vanwersch, W C Kuijpers, H C Trap, I HC Philippens, and H P Benschop, “Low levels of sarin affect the EEG in marmoset monkeys: a pilot study,” Journal of Applied Toxicology, vol. 24, no. 6, pp. 475–483, 2004.
- F H Duffy, J L Burchfiel, P H Bartels, M Gaon, and V M Sim, “Long-term effects of an organophosphate upon the human electroencephalogram,” Toxicology and Applied Pharmacology, vol. 47, no. 1, pp. 161–176, 1979.
- X O Shu, M S Linet, R N Gao, et al., “Chloramphenicol use and childhood leukaemia in Shanghai,” Lancet, vol. 2, no. 8565, pp. 934–937, 1987.
- J P Maurissen and B R Marable, “Neurotoxicity test validation, positive controls and proficiency: are chemicals necessary?,” Neurotoxicology and Teratology, vol. 27, no. 4, pp. 545–551, 2005.
- M B Abou-Donia, “Organophosphorus ester-induced chronic neurotoxicity,” Archives of Environmental Health, vol. 58, no. 8, pp. 484–497, 2003.
- M I Smith and R D Lillie, “The histopathology of triorthocresyl phosphate poisoning. The etiology of so-called ginger paralysis (third report),” Archives of Neurology and Psychiatry, vol. 26, pp. 976–992, 1931.
- P L Bidstrup, J A Bonnell, and A G Beckett, “Paralysis following poisoning by a new organic phosphorus insecticide (mipafox); report on two cases,” British Medical Journal, vol. 1, no. 4819, pp. 1068–1072, 1953.
- M B Abou-Donia, “Organophosphorus ester-induced delayed neurotoxicity,” Annual Review of Pharmacology and Toxicology, vol. 21, pp. 511–548, 1981.
- C Xintaris, J R Burg, S Tanaka, et al., “Occupational exposure to leptophos and other chemicals,” 1978, Washington, DC, DHEW (NIOSH) Publication no.: 78-136. US Government Printing Office.
- M K Johnson, “Delayed neurotoxicity tests of organophosphorus esters: a proposed protocol integrating neuropathy target esterase (NTE) assays with behavior and histopathology tests to obtain more information more quickly from fewer animals,” in Proceedings of the International Congress on Environmental Hazards of Agrochemicals in Developing Countries, vol. 1, pp. 474–493, Alexandria, Egypt, 1983.
- M K Johnson and J M Barnes, “Age and the sensitivity of chicks to the delayed neurotoxic effects on some organophosphorus compounds,” Biochemical Pharmacology, vol. 19, no. 12, pp. 3045–3047, 1970.
- G H De Oliveira, V Moreira, and S PR Goes, “Organophosphate induced delayed neuropathy in genetically dissimilar chickens: studies with tri-ortho-cresyl phosphate (TOCP) and trichlorfon,” Toxicology Letters, vol. 136, no. 2, pp. 143–150, 2002.
- Parkinson's Disease Foundation. 2004. Symptoms, http://www.pdf.org/AboutPD/symptoms.cfm.
- T M Dawson and V L Dawson, “Molecular pathways of neurodegeneration in Parkinson's disease,” Science, vol. 302, no. 5646, pp. 819–822, 2003.
- C M Tanner, R Ottman, S M Goldman, et al., “Parkinson disease in twins: an etiologic study,” Journal of the American Medical Association, vol. 281, no. 4, pp. 341–346, 1999.
- A A Li, P J Mink, L J McIntosh, M J Teta, and B Finley, “Evaluation of epidemiologic and animal data associating pesticides with Parkinson's disease,” Journal of Occupational and Environmental Medicine, vol. 47, no. 10, pp. 1059–1087, 2005.
- V N Uversky, “Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration,” Cell and Tissue Research, vol. 318, no. 1, pp. 225–241, 2004.
- J Bové, D Prou, C Perier, and S Przedborski, “Toxin-induced models of Parkinson's disease,” NeuroRx, vol. 2, no. 3, pp. 484–494, 2005.
- S M Fleming, P-O Fernagut, and M-F Chesselet, “Genetic mouse models of Parkinsonism: strengths and limitations,” NeuroRx, vol. 2, no. 3, pp. 495–503, 2005.
- M-F Chesselet, “Animal models of neurological disorders (an editorial),” NeuroRx, vol. 2, no. 3, p. 395, 2005.
- J R Richardson, Y Quan, T B Sherer, J T Greenamyre, and G W Miller, “Paraquat neurotoxicity is distinct from that of MPTP and rotenone,” Toxicological Sciences, vol. 88, no. 1, pp. 193–201, 2005.
- M Thiruchelvam, E K Richfield, B M Goodman, R B Baggs, and D A Cory-Slechta, “Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype,” NeuroToxicology, vol. 23, no. 4-5, pp. 621–633, 2002.
- P J Landrigan, B Sonawane, R N Butler, L Trasande, R Callan, and D Droller, “Early environmental origins of neurodegenerative disease in later life,” Environmental Health Perspectives, vol. 113, no. 9, pp. 1230–1233, 2005.
- G Logroscino, “The role of early life environmental risk factors in Parkinson disease: what is the evidence?,” Environmental Health Perspectives, vol. 113, no. 9, pp. 1234–1238, 2005.
- M Gatz, C A Reynolds, L Fratiglioni, et al., “Role of genes and environments for explaining Alzheimer disease,” Archives of General Psychiatry, vol. 63, no. 2, pp. 168–174, 2006.
- T L Spires and B T Hyman, “Transgenic models of Alzheimer's disease: learning from animals,” NeuroRx, vol. 2, no. 3, pp. 423–437, 2005.
- N Scarmeas, S M Albert, J J Manly, and Y Stern, “Education and rates of cognitive decline in incident Alzheimer's disease,” Journal of Neurology, Neurosurgery and Psychiatry, vol. 77, no. 3, pp. 308–316, 2006.
- T Schneider and R Przewlocki, “Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism,” Neuropsychopharmacology, vol. 30, no. 1, pp. 80–89, 2005.
- K Miyaki, Y Nishiwaki, K Maekawa, et al., “Effects of sarin on the nervous system of subway workers seven years after the Tokyo subway sarin attack,” Journal of Occupational Health, vol. 47, no. 4, pp. 299–304, 2005.
- T Kawada, M Katsumata, H Suzuki, et al., “Insomnia as a sequela of sarin toxicity several years after exposure in Tokyo subway trains,” Perceptual and Motor Skills, vol. 100, no. 3 II, pp. 1121–1126, 2005.
- T Ohtani, A Iwanami, K Kasai, et al., “Post-traumatic stress disorder symptoms in victims of Tokyo subway attack: a 5-year follow-up study,” Psychiatry and Clinical Neurosciences, vol. 58, no. 6, pp. 624–629, 2004.