- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2007 (2007), Article ID 65136, 8 pages
Effect of Fluid Shear Stress on Endocytosis of Heparan Sulfate and Low-density Lipoproteins
1Department of Biomedical Engineering, George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta 30332, GA, USA
2Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala 75123, Sweden
3Biotechnology and Genetics program, College of Natural Resources, Virginia Polytechnic Institute and State University, Blacksburg 24061, VA, USA
Received 30 April 2007; Revised 9 October 2007; Accepted 11 December 2007
Academic Editor: Ali A. Khraibi
Copyright © 2007 Irmeli Barkefors et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- D. P. Giddens, C. K. Zarins, and S. Glagov, “The role of fluid mechanics in the localization and detection of atherosclerosis,” Journal of Biomechanical Engineering, vol. 115, no. 4 B, pp. 588–594, 1993.
- D. N. Ku, D. P. Giddens, D. J. Phillips, and D. E. Strandness Jr., “Hemodynamics of the normal human carotid bifurcation: in vitro and in vivo studies,” Ultrasound in Medicine and Biology, vol. 11, no. 1, pp. 13–26, 1985.
- D. N. Ku, D. P. Giddens, C. K. Zarins, and S. Glagov, “Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low and oscillating shear stress,” Arteriosclerosis, vol. 5, no. 3, pp. 293–302, 1985.
- M. Y. Pahakis, J. R. Kosky, R. O. Dull, and J. M. Tarbell, “The role of endothelial glycocalyx components in mechanotransduction of fluid shear stress,” Biochemical and Biophysical Research Communications, vol. 355, no. 1, pp. 228–233, 2007.
- S. Weinbaum, X. Zhang, Y. Han, H. Vink, and S. C. Cowin, “Mechanotransduction and flow across the endothelial glycocalyx,” Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 13, pp. 7988–7995, 2003.
- M. M. Thi, J. M. Tarbell, S. Weinbaum, and D. C. Spray, “The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: a “bumper-car” model,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 47, pp. 16483–16488, 2004.
- M. Gouverneur, B. Van Den Berg, M. Nieuwdorp, E. Stroes, and H. Vink, “Vasculoprotective properties of the endothelial glycocalyx: effects of fluid shear stress,” Journal of Internal Medicine, vol. 259, no. 4, pp. 393–400, 2006.
- J. A. Florian, J. R. Kosky, K. Ainslie, Z. Pang, R. O. Dull, and J. M. Tarbell, “Heparan sulfate proteoglycan is a mechanosensor on endothelial cells,” Circulation Research, vol. 93, no. 10, pp. e136–142, 2003.
- M. Gouverneur, J. A. E. Spaan, H. Pannekoek, R. D. Fontijn, and H. Vink, “Fluid shear stress stimulates incorporation of hyaluronan into endothelial cell glycocalyx,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 290, no. 1, pp. H458–H462, 2006.
- G. Hu, A. T. Place, and R. D. Minshall, “Regulation of endothelial permeability by Src kinase signaling: vascular leakage versus transcellular transport of drugs and macromolecules,” Chemico-Biological Interactions. In press.
- A. Ueda, M. Shimomura, M. Ikeda, R. Yamaguchi, and K. Tanishita, “Effect of glycocalyx on shear-dependent albumin uptake in endothelial cells,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 287, pp. H2287–H2294, 2004.
- H. Jo, R. O. Dull, T. M. Hollis, and J. M. Tarbell, “Endothelial albumin permeability is shear dependent, time dependent, and reversible,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 260, p. 5, 1991.
- B. M. Van Den Berg, J. A. E. Spaan, T. M. Rolf, and H. Vink, “Atherogenic region and diet diminish glycocalyx dimension and increase intima-to-media ratios at murine carotid artery bifurcation,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 290, no. 2, pp. H915–H920, 2006.
- T. Arisaka, M. Mitsumata, M. Kawasumi, T. Tohjima, S. Hirose, and Y. Yoshida, “Effects of shear stress on glycosaminoglycan synthesis in vascular endothelial cells,” Annals of the New York Academy of Sciences, vol. 748, no. 1, pp. 543–554, 1995.
- L. M. Cancel, A. Fitting, and J. M. Tarbell, “In vitro study of LDL transport under pressurized (convective) conditions,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 293, no. 1, pp. H126–H132, 2007.
- E. A. Sprague, B. L. Steinbach, R. M. Nerem, and C. J. Schwartz, “Influence of a laminar steady-state fluid-imposed wall shear stress on the binding, internalization, and degradation of low-density lipoproteins by cultured arterial endothelium,” Circulation, vol. 76, no. 3, pp. 648–656, 1987.
- M. Traoré, R. J. Sun, and S. Fawzi-Grancher, et al., “Kinetics of the endocytotic pathway of low density lipoprotein (LDL) in human endothelial cells line under shear stress: an in vitro confocal microscopy study,” Clinical Hemorheology and Microcirculation, vol. 33, no. 3, pp. 243–251, 2005.
- M. Mulder, P. Lombardi, H. Jansen, T. J. C. Van Berkel, R. R. Frants, and L. M. Havekes, “Low density lipoprotein receptor internalizes low density and very low density lipoproteins that are bound to heparan sulfate proteoglycans via lipoprotein lipase,” Journal of Biological Chemistry, vol. 268, no. 13, pp. 9369–9375, 1993.
- M. S. Brown and J. L. Goldstein, “Receptor-mediated endocytosis: insights from the lipoprotein receptor system,” Proceedings of the National Academy of Sciences of the United States of America, vol. 76, no. 7, pp. 3330–3337, 1979.
- E. Vasile, M. Simionescu, and N. Simionescu, “Visulaization of the binding, endocytosis and transcytosis of low-density lipoprotein in the arterial endothelium in situ,” Journal of Cell Biology, vol. 96, pp. 1677–1689, 1983.
- W. Duan, L. Paka, and S. Pillarisetti, “Distinct effects of glucose and glucosamine on vascular endothelial and smooth muscle cells: evidence for a protective role for glucosamine in atherosclerosis,” Cardiovascular Diabetology, vol. 4, p. 16, 2005.
- D. Steinberg, “Low denisty lipoprotein oxidation and its pathological significance,” The Journal of Biological Chemistry, vol. 272, no. 34, p. 4, 1997.
- A. C. Carr, M. R. McCall, and B. Frei, “Oxidation of LDL by myeloperoxidase and reactive oxygene species: reaction pathways and antioxidante protection,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 20, pp. 1716–1723, 2000.
- J. L. Mehta, J. Chen, P. L. Hermonat, F. Romeo, and G. Novelli, “Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders,” Cardiovascular Research, vol. 69, no. 1, pp. 36–45, 2006.
- P. Boucher and M. Gotthardt, “LRP and PDGF signaling: a pathway to atherosclerosis,” Trends in Cardiovascular Medicine, vol. 14, no. 2, pp. 55–60, 2004.