Characterization of Phototransduction Gene Knockouts Revealed Important Signaling Networks in the Light-Induced Retinal Degeneration
Figure 2
Apoptosis map. Expression data of Rhok−/−/Sag−/− mice was overlaid onto a hypothetical apoptosis map using the GenMAPP http://www.genmapp.org program. Each rectangle represents a gene in the pathway. The number on the right of the rectangle corresponds to the log 2 ratio. Genes highlighted in yellow are unchanged. Pink and red denote upregulated genes while dark and light green correspond to downregulated genes. Rhok−/−/Sag−/− mice were exposed to 1 hour of low light () and adapted for the indicated time
period of darkness.
