Metabolic Control Analysis: A Tool for Designing Strategies to Manipulate Metabolic Pathways

Figure 1

Glycolytic pathway and principal branches. GLUT, glucose transporter; HK, hexokinase; PFK-1, phosphofructokinase-1; G6P, glucose-6-phosphate; F1,6BP, fructose 1,6 bisphosphate; DHAP, dihydroxyacetone phosphate; G3P, glyceraldehyde-3-phosphate; 3PG, 3-phosphoglycerate; PEP, phosphoenolpyruvate; pyr, pyruvate; PYK, pyruvate kinase; L-lac, L-lactate; acetal, acetaldehyde; AT, alanine transaminase. S. cerevisiae lacks the LDH gene.