Review Article

Toxoplasma Rhoptries: Unique Secretory Organelles and Source of Promising Vaccine Proteins for Immunoprevention of Toxoplasmosis

Table 1

The participation of secretory organelles proteins in the invasion of the host cell by protozoan Toxoplasma gondii; PV: parasitophorous vacuole, MICs: micronemes proteins, TgAMA1: T. gondii apical membrane antigen 1, RONs: rhoptry neck proteins, ROPs: rhoptry proteins, GRAs: dense granule proteins.

Invasion stageSecretory organelles/secretion process
secreted proteins

AdhesionMicronemes/transient
TgAMA1,TgMICs etc.
Biogenesis of moving junction, PV and its association with host mitochondria and endoplasmic reticulumRhoptries/transient
RONs, ROPs
Formation of the specific architecture and function of PVDense granules/continuous
GRAs