Receptor Guided 3D-QSAR: A Useful Approach for Designing of IGF-1R Inhibitors
Table 3
Statistics of different PLS analysis after region focusing. (GS: geometrical scheme; SE: standard error of estimate; n.: number of components; : Fischer’s value for test of significance; : coefficient of determination after 100 bootstrapping runs; SD: standard deviation; Field contribution: (S) steric field, (E) electrostatic field, (H) hydrophobic field, (D) H-bond donor field, and (A) H-bond acceptor field.).