The pol3-t Hyperrecombination Phenotype and DNA Damage-Induced Recombination in Saccharomyces cerevisiae Is RAD50 Dependent

Table 6

Effect of pol3-t on 𝛾-ray-induced intrachromosomal recombination in RAD ⁺ and rad50∆ strains.

Strain	𝛾-Rays (Gy)	% survival	Intrachromosomal Recombination (×10^−4)
RSY6 (POL3 RAD50)	0	100	2.4 ± 0.1
	50	65 ± 2.5	6.2 ± 0.9^**
	500	29 ± 4.6	18 ± 2.3^***
	1000	5 ± 2.4	39 ± 7.1^***
AGY30 (pol3-t)	0	100	8.3 ± 0.5
	50	60 ± 11	12 ± 1.5*
	500	14 ± 2.5	23 ± 6.5*
	1000	3.8 ± 2.3	31 ± 9.7*
YR50-1 (rad50Δ)	0	100	1.8 ± 0.24
	1	71 ± 13	2.9 ± 0.37^**
	10	46 ± 0.8	3.9 ± 0.38^**
	50	11 ± 2.5	5.7 ± 1.5^***
AGY34 (rad50Δpol3-t)	0	100	1.1 ± 0.16
	1	69 ± 16	3.1 ± 0.97^**
	10	35 ± 12	5.1 ± 2.51^**
	50	5 ± 0.7	6.1 ± 0.8^***

See legend to Table 4.