Modular Cre/lox System and Genetic Therapeutics for Colorectal Cancer
Figure 2
Reporter activity differs from cell death induction. (a) Graph modeling the relationship between luciferase expression and luciferase reporter activity, within the linear range of detection of a luminometer; an essentially linear relationship is depicted. (b) Graph modeling the relationship between concentration of the cell death inducer FADD and probability of cell death for cells in the transfected cell population. An essentially sigmoidal curve is depicted, as the probability of cell death cannot exceed 100% regardless of increasing levels of FADD. For both (a) and (b) arbitrary units of measurement are shown for the purposes of illustration.
