Molecularly Characterised Xenograft Tumour Mouse Models: Valuable Tools for Evaluation of New Therapeutic Strategies for Secondary Liver Cancers

Table 3

Immunohistochemical analyses of human original and corresponding xenograft tumours. CCC: cholangiocellular carcinoma; CRC: colorectal carcinoma; n.a.: not analysed; −: no staining; +: positive staining; ^bsingle stained cells or staining restricted to normal liver cells; orig.: original tumour sample; xeno.: xenograft tumour sample.

Tumour	Diagnosis	CEA orig./xeno.	CK8/18 orig./xeno.	CK20 orig./xeno.
AKH10	Intrahepatic metastatic CCC	+/+	+/+	−/−
AKH23	Liver metastasis of pancreatic cancer	+^b/−	+/+	−/−
AKH47	Intrahepatic CCC	+^b/−	+/+	−/−
KFJ6	CRC liver metastasis	+/+	+/+	+/+
KFJ9	Intrahepatic metastatic CCC	+/+	+/+	+/+
KFJ10	CRC liver metastasis	+/+	+/+	+/+
KFJ12	CRC liver metastasis	+/+	+/+	+/+
KFJ18	CRC liver metastasis	+/+	+/+	+/+
KFJ21	CRC liver metastasis	+/+	+/+	+/+
KFJ25	CRC liver metastasis	+/+	+/+	+/+