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Journal of Biomedicine and Biotechnology
Volume 2009 (2009), Article ID 613879, 13 pages
Effects of Chronic Mild Stress on the Development of Atherosclerosis and Expression of Toll-Like Receptor 4 Signaling Pathway in Adolescent Apolipoprotein E Knockout Mice
1Key Lab for Arteriosclerology of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China
2Department of Pathophysiology, Medical School of Changsha of Hunan Province, Changsha 41000, China
Received 5 March 2009; Revised 9 June 2009; Accepted 10 June 2009
Academic Editor: Terry Delovitch
Copyright © 2009 Hongfeng Gu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- A. Rozanski, J. A. Blumenthal, and J. Kaplan, “Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy,” Circulation, vol. 99, no. 16, pp. 2192–2217, 1999.
- X. H. Xu, P. K. Shah, E. Faure, et al., “Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxLDL,” Circulation, vol. 104, no. 25, pp. 3103–3108, 2001.
- J. R. Kaplan, S. B. Manuck, T. B. Clarkson, et al., “Social stress and atherosclerosis in normocholesterolemic monkeys,” Science, vol. 220, no. 4598, pp. 733–735, 1983.
- A. Bierhaus, J. Wolf, M. Andrassy, et al., “A mechanism converting psychosocial stress into mononuclear cell activation,” Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 4, pp. 1920–1925, 2003.
- A. Rozanski, J. A. Blumenthal, K. W. Davidson, et al., “The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology,” Journal of American College of Cardiology, vol. 45, no. 5, pp. 637–651, 2005.
- E. A. Kaperonis, C. D. Liapis, J. D. Kakisis, et al., “Inflammation and atherosclerosis,” European Journal of Vascular and Endovascular Surgery, vol. 31, no. 4, pp. 386–393, 2006.
- P. Carmeliet, L. Moons, and D. Collen, “Mouse models of angiogenesis, arterial stenosis, atherosclerosis and hemostasis,” Cardiovascular Research, vol. 39, no. 1, pp. 8–33, 1998.
- A. Mullick, P. Tobias, and L. Curtiss, “Toll-like receptors and atherosclerosis,” Immunologic Research, vol. 34, no. 3, pp. 193–209, 2006.
- A. H. Schoneveld, I. Hoefer, J. P. Sluijter, J. D. Laman , D. P. V. de Kleijn, and G. Pasterkamp, “Atherosclerotic lesion development and Toll like receptor 2 and 4 responsiveness,” Atherosclerosis, vol. 197, no. 1, pp. 95–104, 2008.
- Y. Liu, H. Yu, Y. Zhang, et al., “TLRs are important inflammatory factors in atherosclerosis and may be a therapeutic target,” Medical Hypotheses, vol. 70, no. 2, pp. 314–316, 2008.
- S. H. Dirks, S. J. H. van Deventer, and M. P. Peppelenbosch, “Lipopolysaccharide recognition, internalisation, signaling and other cellular effects,” Journal of Endotoxin Research, vol. 7, no. 5, pp. 335–348, 2001.
- K. A. Fitzgerald, E. M. Palsson-McDermott, A. G. Bowie, et al., “Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction,” Nature, vol. 413, no. 6851, pp. 78–83, 2001.
- G. Zhang and S. Ghosh, “Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity,” The Journal of Clinical Investigation, vol. 107, no. 1, pp. 13–19, 2001.
- J. R. Caso, J. M. Pradillo, O. Hurtado, J. C. Leza, M. A. Moro, and I. Lizasoain, “Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke,” Stroke, vol. 39, no. 4, pp. 1314–1320, 2008.
- J. Lewthwaite, N. Owen, A. Coates, et al., “Circulating human heat shock protein 60 in the plasma of British civil servants:relationship to physiological and psychosocial stress,” Circulation, vol. 106, no. 2, pp. 196–201, 2002.
- F. Y. Tanga, N. Nutile-McMenemy, and J. A. DeLeo, “The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy,” Proceedings of the National Academy Sciences of the United States of America, vol. 102, no. 16, pp. 5856–5861, 2005.
- K. A. Matthews, J. F. Owens, L. H. Kuller, et al., “Stress-induced pulse pressure change predicts women's carotid atherosclerosis,” Stroke, vol. 29, no. 8, pp. 1525–1530, 1998.
- C. Kopp, E. Vogel, M. C. Rettori, et al., “The effects of melatonin on the behavioural disturbances induced by chronic mild stress in C3H/He mice,” Behavioural Pharmacology, vol. 10, no. 8, pp. 73–83, 1999.
- I. Yalcin, F. Aksu, and C. Belzung, “Effects of desipramine and tramadol in a chronic mild stress mode in mice are altered by yohimbine but not by pindolol,” European Journal of Pharmacology, vol. 514, no. 2-3, pp. 165–174, 2005.
- P. A. Bourassa, P. M. Milost, B. J. Gaynor, J. L. Breslow, and R. J. Aiello, “Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice,” Proceedings of the National Academy Sciences of the United States of America, vol. 93, no. 19, pp. 10022–10027, 1996.
- Y. Zhang, M. Woodruff, J. Miao, et al., “Toll-like receptor 4 mediates chronic restraint stress-induced immune suppression,” Journal of Neuroimmunology, vol. 194, no. 1, pp. 115–122, 2008.
- M. Kumari, C. Grahame-Clarke, N. Shanks, M. Marmot, S. Lightman, and P. Vallance, “Chronic stress accelerates atherosclerosis in the apolipoprotein E deficient mouse,” Stress, vol. 6, no. 4, pp. 297–299, 2003.
- G. Pasterkamp, J. K. Van Keulen, and D. P. De Kleijn, “Role of Toll-like receptor 4 in the initiation and progression of atherosclerotic disease,” European Journal of Clinical Investigation, vol. 34, no. 5, pp. 297–299, 2004.
- M. P. de Winther, E. Kanters, G. Kraal, and M. H. Hofker, “Nuclear factor B signaling in atherogenesis,” Atherosclerosis, Thrombosis, and Vascular Biology, vol. 25, no. 5, pp. 904–914, 2005.
- T. J. Reape and P. H. Groot, “Chemokines and atherosclerosis,” Atherosclerosis, vol. 147, no. 2, pp. 213–225, 1999.
- G. Barillari, L. Albonici, S. Incerpi, et al., “Inflammatory cytokines stimulate vascular smooth muscle cells locomotion and growth by enhancing alpha5beta1 integrin expression and function,” Atherosclerosis, vol. 154, no. 2, pp. 377–385, 2001.
- K. S. Michelsen, M. H. Wong, P. K. Shah, et al., “Lack of toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 29, pp. 10679–10684, 2004.
- Y. I. Miller, S. Viriyakosol, D. S. Worrall, A. Boullier, S. Butler, and J. L. Witztum, “Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 25, no. 6, pp. 1213–1219, 2005.
- A. Čvoro and G. Matić, “Hyperthermic stress stimulates the association of both constitutive and inducible isoforms of 70 kDa heat shock protein with rat liver glucocorticoid receptor,” The International Journal of Biochemistry and Cell Biology, vol. 34, no. 3, pp. 279–285, 2002.
- P. H. Black and L. D. Garbutt, “Stress, inflammation and cardiovascular disease,” Journal of Psychosomatic Research, vol. 52, no. 1, pp. 1–23, 2002.