DNA Damage/Repair and Polymorphism of the hOGG1 Gene in Lymphocytes of AMD Patients

Table 2

The allele and genotype frequencies and odds ratio (OR) of the Ser326Cys polymorphism of the hOGG1 gene in AMD patients and controls with the extent of endogenous oxidative DNA damage higher than the mean for respective group.

Genotype or allele	Controls (𝑛=20)		AMD patients (𝑛=14)		OR (95% PU)
	Number	Frequency	Number	Frequency
Ser/Ser	11	0.55	10	0.71	2.05 (0.48–8.78)
Ser/Cys	9	0.45	4	0.29	0.49 (0.11–2.09)
Cys/Cys	0	—	0	—	—
Ser	31	0.77	24	0.86	1.74 (0.48–6.35)
Cys	9	0.23	4	0.14	0.57 (0.16–2.09)