Curcumin Decreased Oxidative Stress, Inhibited NF-𝜅B Activation, and Improved Liver Pathology in Ethanol-Induced Liver Injury in Rats

Table 1

Summary of steatosis and necroinflammation score in all groups. Data are expressed as the number of rats exhibiting the grade of steatosis or necroinflammation indicated.

Group	Number	Steatosis^a					Necroinflammation^b
		0	1	2	3	4	0	1	2	3
Control	8	8	—	—	—	—	8	—	—	—
Ethanol	8	—	1	6	1	—	—	8	—	—
Ethanol + curI	6	5	1	—	—	—	6	—	—	—
Ethanol + curII	7	4	3	—	—	—	3	4	—	—

^aThe severity of steatosis was grade by the following. 0 = no parenchymal cells containing fat, 1 = <20% of parenchymal cells containing fat, 2 = 20–39% of parenchymal cells containing fat, 3 = 40–50% of parenchymal cells containing fat, 4 = >51% of parenchymal cells containing fat. ^bThe severity of necroinflammation was grade by the following. 0 = no inflammation and necrosis under low-power field, 1 = 1 focus per low-power field, 2 = 2 foci per low-power field, 3 = 3 or more foci per low-power field.