Review Article

Optical Spectroscopy for Noninvasive Monitoring of Stem Cell Differentiation

Figure 3

IR spectral analysis of a small intestinal crypt using synchrotron FTIR microspectroscopy. (a) Ten IR spectra of the entire biochemical-cell fingerprint region (900 to 1,800 cm−1) acquired from the assigned transit-amplifying location (locations 1–3; black lines, top), the putative stem cell location (locations 4–6; red lines, middle), and the differentiated location (locations 7–10; blue lines, bottom). (b) PC analysis of a small intestinal crypt’s IR spectra using the entire biochemical-cell fingerprint region. Reprinted with permission from [39] (Copyright AlphaMed press 2008).
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