Construction and Characterization of a Novel Fusion Protein MG7-scFv/SEB against Gastric Cancer

<table>Production of cytokines by stimulated PBMCs: (a) IFN-<i>γ</i> production, (b) IL-2 production, (c) IL-4 production, (d) IL-10 production. The productions of IFN-<i>γ</i> and IL-2 are much more than those of IL-4 and IL-10 (<svg height="11.25" id="M31" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 48.337502 11.25" width="48.337502" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.25)">
<g transform="translate(72,-63)">
<text transform="matrix(1,0,0,-1,-71.95,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="26.056252" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">5</tspan>
</text>
</g>
</g>
</svg>). It indicated that SEB mainly activates Th1 cell to upregulate cellular immunity; meanwhile, it slightly activates Th2 cell.</table>

BioMed Research International

fig6

Figure 6

Figure 6: Construction and Characterization of a Novel Fusion Protein MG7-scFv/SEB against Gastric Cancer 