Epo Is Relevant Neither for Microvascular Formation Nor for the New Formation and Maintenance of Mice Skeletal Muscle Fibres in Both Normoxia and Hypoxia

Figure 3

Quantitative determination of (a) activated HIF-𝛼 protein and (b) HIF-𝛼 mRNA and (c) VEGF protein in the gastrocnemius muscle of wild-type (WT) and Epo-TAg^h mice in normoxia (Nx) and following acute hypoxia for 24 hours (AHx) and chronic hypoxia for 14 days (CHx). Values are means ± SD. *, significantly different from corresponding Nx group, 𝑃<.01. #, significantly different from corresponding WT group, 𝑃<.05. &, significantly different from corresponding AHx group. #, 𝑃<.05.

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(b)

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