Cysteine-Free Proteins in the Immunobiology of Arthropod-Borne Diseases

Table 1

Abundance of proteins devoid of cysteine residues (CFP) or tryptophan residues (WFP), included those predicted as secreted (sCFP and sWFP), in 12 species of arthropod-borne microorganisms.

Species	Proteins∗	CFP (%)	WFP (%)	sCFP	sWFP	sCFP/sWFP
Alphaproteobacteria
A. phagocytophilum HZ	1264	12 (0.94)	77 (6.09)	7	20	0.35
O. tsutsugamushi str. Boryong	1182	15 (1.26)	71 (6.00)	3	8	0.37
E. chaffeensis str. Arkansas	1105	20 (1.80)	133 (12.03)	12	34	0.35
R. rickettsii str. “Sheila Smith”	1345	40 (2.97)	99 (7.36)	14	21	0.66
W. endosymbiont of D. melanogaster	1195	36 (3.01)	90 (7.53)	13	14	0.92
B. bacilliformis KC583	1282	86 (6.70)	74 (5.76)	43	12	3.58
Gammaproteobacteria
W. glossinidia endosymbiont of G. brevipalpis	611	26 (4.25)	71 (11.62)	6	6	1.00
F. tularensis subsp. tularensis FSC198	1605	78 (4.85)	133 (8.28)	54	19	2.84
C. burnetii RSA 493	2016	114 (5.65)	78 (3.86)	63	12	5.25
Y. pestis Nepal 516	3981	339 (8.51)	157 (3.94)	216	32	6.75
Spirochaetes
B. burgdorferi B31	851	140 (16.45)	138 (16.21)	89	36	2.47
Apicomplexa
P. falciparum 3D7	5267	64 (1.21)	567 (10.76)	26	115	0.22

∗Chromosomal proteins only.