Research Article

Pretreatment with Cry1Ac Protoxin Modulates the Immune Response, and Increases the Survival of Plasmodium-Infected CBA/Ca Mice

Figure 5

Parasite-specific antibody responses in mice treated with Cry1Ac and infected with P. berghei ANKA. Mice were treated with Cry1Ac protoxin or PBS as described previously and were infected with P. berghei ANKA. At days 4 (white bars) and 8 (grey bars) PI, the sera of three mice from each group were collected and measured by ELISA for antibody levels. The results are expressed as the mean OD value ± SD ( 𝑛 = 3 ) . Control absorbance values were provided by normal mouse serum (NS) obtained from age- and sex-matched CBA/Ca mice. Data are representative of two separate experiments. Asterisks indicate statistically significant differences between the indicated groups.
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