Association of TNFAIP3 Polymorphism with Susceptibility to Systemic Lupus Erythematosus in a Japanese Population
Table 2
Association of TNFAIP3 rs2230926 with presence or absence of nephritis.
rs2230926
Genotype
Allele
Allelic association
Recessive
Dominant
G/G
T/G
T/T
G
OR (95%CI)
OR (95%CI)
OR (95%CI)
SLE
โwith nephritis ()
4(2.4)
33(19.6)
131(78.0)
41(12.2)
.010
1.70 (1.13โ2.56)
.022
10.8 (1.85โ63.2)
.035
1.62 (1.03โ2.53)
โwithout nephritis ()
2(1.4)
21(14.5)
122(84.1)
25(8.6)
.55
1.16 (0.72โ1.87)
.15
6.20 (0.75โ51.1)
.77
1.08 (0.64โ1.81)
โControls ()
1(0.2)
65(14.6)
378(85.1)
67(7.5)
reference
reference
reference
OR: odds ratio, 95%CI: confidence interval. Parentheses in the genotype and allele frequency columns indicate percentages. and dominant models for the G allele.