Association of TNFAIP3 Polymorphism with Susceptibility to Systemic Lupus Erythematosus in a Japanese Population

Table 2

Association of TNFAIP3 rs2230926 with presence or absence of nephritis.

rs2230926	Genotype			Allele	Allelic association		Recessive model^∗		Dominant model^∗
	G/G	T/G	T/T	G	𝑃	OR (95%CI)	𝑃	OR (95%CI)	𝑃	OR (95%CI)
SLE
with nephritis (𝑛=168)	4(2.4)	33(19.6)	131(78.0)	41(12.2)	.010	1.70 (1.13–2.56)	.022	10.8 (1.85–63.2)	.035	1.62 (1.03–2.53)
without nephritis (𝑛=145)	2(1.4)	21(14.5)	122(84.1)	25(8.6)	.55	1.16 (0.72–1.87)	.15	6.20 (0.75–51.1)	.77	1.08 (0.64–1.81)
Controls (𝑛=444)	1(0.2)	65(14.6)	378(85.1)	67(7.5)		reference		reference		reference

OR: odds ratio, 95%CI: confidence interval. Parentheses in the genotype and allele frequency columns indicate percentages.
^∗Recessive and dominant models for the G allele.