Assessment of the Genetic Diversity of Mycobacterium tuberculosis esxA, esxH, and fbpB Genes among Clinical Isolates and Its Implication for the Future Immunization by New Tuberculosis Subunit Vaccines Ag85B-ESAT-6 and Ag85B-TB10.4
Table 1
Genotyping data of the 88 study isolates of M. tuberculosis that were originated from Arkansas, USA, and Turkey.
Isolate no.
IS6110 Copy no.
IS6110 RFLP Pattern ¥
Spoligotype
Isolate no.
IS6110 Copy no.
IS6110 RFLP Pattern ¥
Spoligotype
SA143
14
01046
000000000003771
SA208
03
00370
700036777760471
SA033
18
01063
000000000003771
SA738
07
05660
777777744720771
SA604
18
04495
000000000003771
SA204
10
00636
074377607760700
SA327
21
00237
000000000003771
SA565
09
01321
377737774020731
SA374
22
02623
000000000003771
SA710
17
02661
737377677760771
SA413
22
02660
000000000003771
SA221
01
00129
774377777413771
SA193
14
00638
677737607760771
SA253
14
00619
776377613760771
SA759
12
05774
677777477413771
SA052
03
00403
777776777560601
SA639
15
04804
703777740003771
SA333
04
01658
777776777560601
SA085
11
01336
776177607760771
SA597
07
04433
777776777760761
SA557
11
04222
776177607760771
SA286
08
01330
777777000020771
SA378
09
02620
777777770000000
SA198
03
00370
777777777613771
SA652
08
01646
777777774020771
SA173
19
00401
Not Available
SA053
11
00499
777777774020771
TK035
09
TK035
000000004020771
SA475
05
04430
777777777720771
TK036
08
TK036
000000007760771
SA010
09
00472
777777777720771
ZD073
15
ZD073
703777740003031
SA637
10
04802
777777777720771
TK013
03
TK013
777777404760771
SA213
13
00640
777777777720771
TK091
03
TK091
777777404760771
SA364
13
00807
777777777720771
TK110
08
TK110
777777740460771
SA025
11
00325
777777777760731
ZD039
08
ZD039
777777774020771
SA310
10
00315
776177607760771
ZD056
09
ZD056
777777774020771
SA285
06
01329
777777777760771
ZD061
08
ZD061
777777777720771
SA169
09
00326
777777777760771
ZD063
08
ZD063
777777777720771
SA120
12
00372
777777777760771
ZD034
09
ZD034
777777777720771
SA102
12
00538
777777777760771
TK086
10
TK086
777777777720771
SA471
14
06474
777777777760771
ZD013
10
ZD013
777777777720771
SA131
15
00627
777777777760771
ZD020
11
ZD020
777777777720771
SA157
06
00314
777777557760771
ZD071
11
ZD071
777777777720771
SA030
13
00570
777777607560771
TK065
05
TK065
777777777760771
SA706
10
05458
777777777760471
TK103
08
TK103
777777777760771
SA111
02
00016
777776777760771
TK095
09
TK095
777777777760771
SA352
03
00064
777776777760771
ZD062
09
ZD062
777777777760771
SA019
04
00432
777776777760771
TK030
10
TK030
777777777760771
SA170
06
00327
777776777760771
TK105
11
TK105
777777777760771
SA341
03
00694
777776777760601
ZD093
13
ZD093
757777777760771
SA020
05
00392
777776777760601
TK003
06
TK003
037637777760771
SA596
07
04432
777776777760601
ZD041
06
ZD041
777777764020731
SA526
01
00195
777777776413771
ZD031
09
ZD031
717777777760771
SA162
04
00319
700076777760700
ZD024
09
ZD024
770000770000000
SA778
08
06019
376177607760771
TK007
08
TK007
777767777760671
SA038
11
00496
777777777320771
TK016
07
TK016
037227760160771
SA512
12
00832
776377770760771
TK011
08
TK011
700377777760771
SA189
13
00598
777763777760771
TK112
09
TK112
777207777777661
SA430
01
00129
763777777413771
TK097
05
TK097
Not Available
numbers starting with SA refer to strains from Arkansas, USA. Isolate numbers starting with ZD or TK refer to strains from Turkey. ¥ The IS6110 RFLP patterns of the Arkansas strains were indicated using the national designations assigned by the National Tuberculosis Genotyping and Sentinel Surveillance Network Program of the Centers for Disease Control and Prevention. The IS6110 RFLP patterns of the Turkish strains were designated using the isolate number in which a given IS6110 RFLP pattern was observed for the first time.