Bioassay-Guided Evaluation of Antinociceptive Effect of N-Salicyloyltryptamine: A Behavioral and Electrophysiological Approach

Table 3

Effect of NST or diazepam on the Rota-rod test.

Treatment	Time (s) on Rota-rod/210 sa
	30 min	60 min	90 min
Vehicle	210.0 ± 0.0	195.3 ± 4.8	210.0 ± 0.0
NST (100 mg/kg)	189.9 ± 5.1	181.5 ± 7.4	210.0 ± 0.0
NST (200 mg/kg)	195.3 ± 5.8	210.0 ± 0.0	179.8 ± 9.3
Diazepam (3 mg/kg)	38.7 ± 9.7b	17.2 ± 11.3b	23.5 ± 15.9b

The motor response was recorded for the following 210 s after drug treatment, n = 10, aValues represent mean ± S.E.M., ^b𝑃<.01 (one-way ANOVA and Dunnett’s test), significantly different from control.