Exploration of the Lysis Mechanisms of Leukaemic Blasts by Chimaeric T-Cells

Figure 5

Specific Lysis of z-CD19 chimaeric effectors is inhibited in the presence of perforin/granzyme inhibitors. Cytolytic activity of effectors was analyzed against SupB15 or Raji cell lines and B-ALL blasts (control) or in the presence of EGTA/MgCl₂ or Concanamycin A.

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