Mechanisms of the Regulation of the Intestinal Na⁺/H⁺Exchanger NHE3

Table 1

Expression of 𝐍𝐚⁺/𝐇⁺ exchangers in the gastrointestinal tract.

	Tissue expression	Cellular distribution	References
NHE1	Ubiquitous, jejunum, ileum, colon, stomach	Basolateral membrane	[21, 122]
NHE2	Jejunum, ileum, colon, stomach	Apical membrane	[19]
NHE3	Jejunum, ileum, colon, stomach	Apical membrane, recycling endosome	[19]
NHE4	Stomach	Basolateral membrane	[28, 39, 123]
NHE5	Brain		[124, 125]
NHE6	Ubiquitous	Recycling endosome	[126]
NHE7	Ubiquitous	Trans-Golgi	[126]
NHE8	Ubiquitous, Jejunum, duodenum, ileum, colon	Apical membrane, recycling endosome	[20, 42, 43, 126, 127]
NHE9	Ubiquitous	Recycling endosome	[126]