Autocrine, Not Paracrine, Interferon-Gamma Gene Delivery Enhances Ex Vivo Antigen-Specific Cytotoxic T Lymphocyte Stimulation and Killing

<table>Structure of the cell treatment protocol.  Shown is the temporal treatment of the Mo/DC and T cells and is self-descriptive.  However, note that AAV/IFN-<i>γ</i> is used to infect Mo/DC at day zero, or naive T cells just prior to coincubation with AAV/antigen-loaded DC on day 5.</table>

BioMed Research International

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Figure 1

Figure 1: Autocrine, Not Paracrine, Interferon-Gamma Gene Delivery Enhances Ex Vivo Antigen-Specific Cytotoxic T Lymphocyte Stimulation and Killing 