Gene Transfer into the Lung by Nanoparticle Dextran-Spermine/Plasmid DNA Complexes

Figure 2

Fluorescent microscopy of GFP expression in COS-7 cell lines transfected with different gene carriers. Fluorescent cells were visualized at 48 h post-transfection. (a) Untreated, (b) naked DNA, (c) PEI/phMGFP, (d) D-SPM/phMGFP at ratio 12, (e) D-SPM/phMGFP at ratio 14, and (f) D-SPM/phMGFP at ratio16. (Magnification x10).

(a)

(b)

(c)

(d)

(e)

(f)