Vaxign: The First Web-Based Vaccine Design Program for Reverse Vaccinology and Applications for Vaccine Development

Table 3

Selected function annotations significantly enriched for UPEC vaccine candidates based on DAVID analysis.

Category	Term	# of Genes	%	P-value	Benjamini  P-value
GO MF^∗	Transport activity	22	45.8	1.8𝐸−14	2.7𝐸−11
Interpro	TonB-dependent receptor, beta-barrel	10	20.8	1.0𝐸−13	4.3𝐸−10
Interpro	Porin, Gram-negative type	8	16.7	1.3𝐸−12	1.8𝐸−9
GO MF	Iron ion transmembrane transporter activity	5	10.4	6.9𝐸−6	1.4𝐸−3
Interpro	Fimbrial biogenesis outer membrane	5	10.4	9.3𝐸−5	4.1𝐸−2

∗: GO MF, the Molecular Function (MF) branch of the Gene Ontology (GO).