Immunological and Therapeutic Strategies against Salmonid Cryptobiosis

Table 1

Infectivity of Cryptobia salmositica to chinook salmon after in vitro exposure to isometamidium chloride to polyclonal antibodies from a recovered fish (reproduced from Ardelli and Woo [59]).

Weeks After Infection	Group 1	Group 2	Group 3	Group 4	Group 5
	PAlC	Drug	PAl	Antibody	Untreated Controls
1	1/10•	7/10	0/10	0/10	8/10
	0.30±0.95■	1.80±2.78	0	0	6.60±4.72
2	1/10	6/10	2/10	0/10	10/10
	0.30±0.95	8.10±5.28	1.80±3.91	0	48,750±45,814
3	2/10	7/10	2/10	0/10	10/10
	0.50±1.27	33,250±38,207	1,950±4,310	0	35,625±29,978
4	2/10	8/10	3/10	3/10	10/10
	0.30±0.675	302,000±254,142	2,500±5,270	5,558±16,665	5,487,500± 5,439,838
5	2/10	10/10	4/10	4/10	10/10
	0.60±1.58	9,395,000± 16,925,911	54,740±112,499	556,944±1,500,001	3,175,000± 3,639,196
6	1/10	10/10	4/10	4/10	10/10
	3,750±11,858	13,475,000±15,298,624	503,750±1,030,810	2,600,000±5,577,465	3,243,750±5,416,196
7	1/10	10/10	4/10	4/10	10/10
	11,250±35,575	18,305,000±52,500,000	928,860±1,326,575	44,383,334±129,150,260	27,051,250±56,209,714

● Number of infected fish/number of fish inoculated.
■ Mean parasitaemia ± standard deviation, determined by HCT or haemacytometer.