Acute, Multiple-Dose Dermal and Genetic Toxicity of Nu-3: A Novel Antimicrobial Agent
Table 2
Absolute and relative organ weights of rats in 28-day dermal toxicity study of Nu-3.
Organs
Nu-3*
Saline
Day 29
Day 43
Day 29
Day 43
Liver
Absolute weight
17.40 ± 18.13
16.33 ± 13.14
15.96 ± 1.40
18.73 ± 0.57
Relative weight*
3.25 ± 0.13
3.45 ± 0.17
3.24 ± 0.07
4.17 ± 0.16
Spleen
Absolute weight
0.70 ± 0.03
0.73 ± 0.00
0.73 ± 0.00
0.73 ± 0.01
Relative weight
0.13 ± 0.00
0.16 ± 0.00
0.15 ± 0.00
0.16 ± 0.00
Kidney
Absolute weight
3.43 ± 0.50
3.1 ± 0.31
3.20 ± 0.12
3.13 ± 0.02
Relative weight
0.65 ± 0.00
0.66 ± 0.00
0.645 ± 0.00
0.70 ± 0.00
*The concentration of Nu-3 was 100 mg/ml. The relative weight was calculated as percentage of the organ to body weight. The data was expressed as average ±SD.
