Differential Expression of MicroRNAs between Eutopic and Ectopic Endometrium in Ovarian Endometriosis

Table 8

Molecular networks constituted by the common differentially expressed transcripts in ovarian and peritoneal endometriosis predicted to be targets of the 50 miRNAs. Differentially expressed genes common to both ovarian and peritoneal endometriosis that are predicted targets of the 50 differentially expressed miRNAs were uploaded in IPA in order to identify the molecular networks and functions to which they belong. 𝑃<.01.

ID	Molecules in Network	𝑃-value	Focus Molecules	Top Functions
1	CAV1, CAV2, CDKN1A, ESR1, HMGA1, LPL, MMP2, NOS3, SMARCA4, SP1, SP3, SRC, TNFSF12, TP53	10E−8	4	Cancer, Cell Cycle, Reproductive System Disease
2	MBD1, SLCO3A1	10E−2	1	Lipid Metabolism, Molecular Transport, Small Molecule Biochemistry
3	RGS2, TNF	10E−2	1	Lipid Metabolism, Small Molecule Biochemistry, Cell Signaling
4	DMD, DTNA, DTNB	10E−2	1	Cellular Assembly and Organization, Nervous System Development and Function, Skeletal and Muscular System Development and Function
5	FYB, GRB2, SKAP2	10E−2	1	Cell-To-Cell Signaling and Interaction, Cell-mediated Immune Response, Cellular Growth and Proliferation