BioMed Research International

Research Article

High-Sensitivity C-Reactive Protein: An Independent Risk Factor for Left Ventricular Hypertrophy in Patients with Lupus Nephritis

Table 2

Laboratory parameters of LN patients grouped by hs-CRP level.
Baseline characteristicsCRP ≥ 3 mg/dl ( 𝑛 = 1 9 8 )CRP < 3 mg/dl ( 𝑛 = 8 9 )
Gender, male, %8.598.98
Age, y 3 9 . 3 7 ± 1 4 . 0 9 ∗ 3 4 . 9 7 ± 1 1 . 5 6
BMI, kg/m2 2 2 . 2 9 ± 3 . 1 8 2 1 . 6 7 ± 3 . 0 7
Smoke history, %18.1816.86
SBP, mmHg 1 3 2 . 9 0 ( 1 2 0 . 0 0 - 1 4 8 . 1 0 ) 1 3 0 . 0 0 ( 1 1 7 . 5 0 - 1 5 0 . 0 0 )
DBP, mmHg 8 6 . 0 0 ( 7 9 . 5 0 - 9 4 . 4 0 ) 8 3 . 5 0 ( 7 3 . 7 5 - 9 0 . 0 0 )
MABP, mmHg 1 0 3 . 3 3 ( 9 0 . 0 0 - 1 1 0 . 6 4 ) 9 7 . 5 ( 8 9 . 0 8 - 1 1 0 . 8 3 )
Hemoglobin level, g/L 9 3 . 0 4 ± 2 4 . 9 1 ∗ ∗ 1 0 6 . 5 7 ± 2 3 . 6 5
ESR, mm/h 5 6 . 0 0 ( 3 1 . 5 0 - 8 3 . 0 0 ) ∗ ∗ 3 2 . 0 0 ( 1 9 . 7 5 - 5 8 . 5 0 )
Serum albumin, g/L 2 7 . 7 0 ± 7 . 0 3 3 3 . 0 9 ± 6 . 9 5
Triglyceride, mmol/L 2 . 4 8 ± 1 . 3 2 2 . 4 6 ± 1 . 0 6
Cholesterol, mmol/L 5 . 6 0 ± 1 . 8 9 ∗ 6 . 4 1 ± 2 . 7 6
Lipoprotein(a), mg/L 2 7 5 . 9 9 ± 2 8 . 9 0 2 8 1 . 1 5 ± 3 1 . 1 6
GFR, ml/min/1.73 m2 7 3 . 4 5 ± 4 . 6 2 8 2 . 1 1 ± 5 . 7 5
Uric acid, mmol/L 4 6 3 . 9 6 ± 1 7 . 8 5 4 2 1 . 4 0 ± 1 9 . 4 8
Calcium, mmol/L 2 . 0 4 ± 0 . 2 2 2 . 1 2 ± 0 . 1 6
Phosphate, mmol/L 1 . 6 8 ± 0 . 8 0 1 . 5 3 ± 0 . 2 9
24 hours urine protein, g/24 h 3 . 0 0 ± 2 . 6 2 3 . 3 7 ± 2 . 2 7
ds-DNA (%)124 (88.57)53 (88.33)
ANA (%)148 (91.36)73 (94.81)
ACL (%)20 (20.00)9 (16.98)
Complement C3, g/L 0 . 4 4 ( 0 . 3 4 - 0 . 7 6 ) 0 . 4 3 ( 0 . 3 2 - 0 . 6 4 )
Fibrinogen, g/L 4 . 1 7 ± 1 . 6 0 ∗ ∗ 3 . 5 4 ± 1 . 1 2
SBP: systolic blood pressure; DBP: diastolic blood pressure; MABP: mean arterial blood pressure; ESR: erythrocyte sedimentation rate; GFR: glomerular filtration rate; ANA: antinuclear antibody; ACL: antiphospholipid antibody. Case number and positive incidence of ds-DNA, ANA and ACL was presented here in the table. Compared with hs-CRP ≥ 3 mg/L, ∗ 𝑃 < . 0 5 , ∗ ∗ 𝑃 < . 0 1 .