Computational Method for Estimating DNA Copy Numbers in Normal Samples, Cancer Cell Lines, and Solid Tumors Using Array Comparative Genomic Hybridization
Figure 3
(a) Signal intensity of SNPs ( axis) for ovarian cancer cell line OVCAR8 before adjustment on genome size. (b) Fraction of SNPs ( axis) with a certain signal intensity ( axis) for ovarian cancer cell line OVCAR8 (see (a)). (c) CN solution for ovarian cancer cell line OVCAR8 after adjustment on genome size .